PhD Dissertation Defense: Harley Edwards
Location
Public Policy : 206
Date & Time
July 29, 2025, 10:00 am – 1:00 pm
Description
Harley Edwards, Ph.D. Candidate
Advisor:
Mark Marten
Title: Synthetic and Systems Biology in Fungi
Abstract:
Genetic engineering through synthetic biology, and systems biology through omics data analysis, are two areas of research which have potential applications in all domains of life. These fields encompass the entire search space of biological life, where genotypic possibilities and combinatorial molecular interactions are greater in number than there are humans on this planet. This work examines novel frontiers in both technologies in the scope of fungal host-cell platforms, with the hope of developing new knowledge and protocols which have potential applications in all of biology. Chapters 2 and 3 are studies in synthetic biology in Y. lipolytica, where chapters 4 and 5 are studies involving systems biology in A. nidulans. Chapters 2 and 4 are computationally focused, whereas chapters 3 and 5 focus on biological phenomena. Together, these chapters will introduce you to the research development cycle of synthetic and systems biology, from synthetic gene network simulation and genetic pathway manipulation to systems scale data analysis used for data driven hypotheses in fungal systems biology.
LOCATION: Public Policy Building - Room 206
AGENDA:
11:45 am EST - Welcome / Room Opens
12:00 pm EST - Presentation followed by questions from the audience.
After the questions from the public, the meeting will be closed for the committee discussion.
Google Meet for virtual attendance: PhD Defense Committee: Harley Edwards
Video call link: https://meet.google.com/cjg-iirf-cmo
Or dial: (US) +1 470-210-1386 PIN: 656 310 358#
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