Dipanjan Pan



Contact Information

UMBC Office
ILSB, Room 322

UMB Office
HSF-III, Room 8179

Pan Lab website


Postdoc. Chemistry/Polymer/Nanotechnology– Washington University in St Louis, 2005

Ph.D. Chemistry – Indian Institute of Technology, Kharagpur, 2002
M.S. Chemistry – Vidyasagar University, 1997

Research Interests

Dipanjan Pan is leading the Laboratory for Materials in Medicine (MatMed) at UMB and UMBC. MatMed’s mission is to develop next generation translatable technologies to improve human health by uniquely merging ‘molecule making’ and ‘device making’, and through innovations in nanomedicine tools and point-of-care diagnostic systems. Active research themes include:

  • Fundamentals: nanoparticle synthesis, drug discovery and controlled delivery, molecular imaging, biosensing
  • Applications: cancer stem cell, immune-therapeutics, drug-free antimicrobial, disease diagnosis/monitoring, image-guided prototyping

Select Publications – PubMed

Pandit S, Banerjee T, Srivastava I, Nie S, Pan D. Machine Learning Assisted Array-based Biomolecular Sensing Using Surface Functionalized Carbon Dots. ACS Sens. 2019 (ASAP)

Srivastava I, Khamo JS, Subhendu P, Fathi P, Huang X, Cao A, Haasch RT, Nie S, Zhang K, Pan D. Influence of Electron Acceptor and Electron Donor on the Photophysical Properties of Carbon Dots. A Comparative Investigation at the Bulk-State and Single-Particle Level. Adv. Funct. Mater. 2019, 1902466.

Fathi P, Knox HJ, Sar D, Tripathi I, Ostadhossein F, Misra SK, Esch MB, Chan J, Pan D. Biodegradable Biliverdin Nanoparticles for Efficient Photoacoustic Imaging. ACS Nano. 2019 Jul 23;13(7):7690-7704.

Datta S, Misra SK, Saha ML, Lahiri N, Louie J, Pan D, Stang PJ. Orthogonal self-assembly of an organoplatinum(II) metallacycle and cucurbit[8]uril that delivers curcumin to cancer cells. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8087-8092.

Ye M, Misra SK, De AK, Ostadhossein F, Singh K, Rund L, Schook L, Pan D. Design, Synthesis, and Characterization of Globular Orphan Nuclear Receptor Regulator with Biological Activity in Soft Tissue Sarcoma. J Med Chem. 2018 Dec 13;61(23):10739-10752.

Ostadhossein F, Misra SK, Tripathi I, Kravchuk V, Vulugundam G, LoBato D, Selmic LE, Pan D. Dual purpose hafnium oxide nanoparticles offer imaging Streptococcus mutans dental biofilm and fight it In vivo via a drug free approach. Biomaterials. 2018 Oct;181:252-267.

Misra SK, De A, Pan D. Targeted Delivery of STAT-3 Modulator to Breast Cancer Stem-Like Cells Downregulates a Series of Stemness Genes. Mol Cancer Ther. 2018 Jan;17(1):119-129.

Misra SK, Dighe K, Schwartz-Duval AS, Shang Z, Labriola LT, Pan D. In situ plasmonic generation in functional ionic-gold-nanogel scaffold for rapid quantitative bio-sensing. Biosens Bioelectron. 2018 Nov 30;120:77-84.

Khan MS, Misra SK, Dighe K, Wang Z, Schwartz-Duval AS, Sar D, Pan D. Electrically-receptive and thermally-responsive paper-based sensor chip for rapid detection of bacterial cells. Biosens Bioelectron. 2018 Jul 1;110:132-140.

Misra SK, Srivastava I, Tripathi I, Daza E, Ostadhossein F, Pan D. Macromolecularly “Caged” Carbon Nanoparticles for Intracellular Trafficking via Switchable Photoluminescence. J Am Chem Soc. 2017 Feb 8;139(5):1746-1749.

Misra SK, Ostadhossein F, Babu R, Kus J, Tankasala D, Sutrisno A, Walsh KA, Bromfield CR, Pan D. 3D-Printed Multidrug-Eluting Stent from Graphene-Nanoplatelet-Doped Biodegradable Polymer Composite. Adv Healthc Mater. 2017 Jun;6(11).

Misra SK, Ostadhossein F, Daza E, Johnson EV, Pan D. Hyperspectral Imaging Offers Visual and Quantitative Evidence of Drug Release from Zwitterionic‐Phospholipid‐Nanocarbon When Concurrently Tracked in 3D Intracellular Space. Adv. Funct. Mater. 2016; 26: 8031-8041.

Khan MS, Misra SK, Wang Z, Daza E, Schwartz-Duval AS, Kus JM, Pan D, Pan D. Paper-Based Analytical Biosensor Chip Designed from Graphene-Nanoplatelet-Amphiphilic-diblock-co-Polymer Composite for Cortisol Detection in Human Saliva. Anal Chem. 2017 Feb 7;89(3):2107-2115.

Misra SK, Ye M, Ostadhossein F, Pan D. Pro-haloacetate Nanoparticles for Efficient Cancer Therapy via Pyruvate Dehydrogenase Kinase Modulation. Sci Rep. 2016 Jun 21;6:28196.

Vulugundam G, Misra SK, Ostadhossein F, Schwartz-Duval AS, Daza EA, Pan D. (-)/(+)-Sparteine induced chirally-active carbon nanoparticles for enantioselective separation of racemic mixtures. Chem Commun (Camb). 2016 Jun 14;52(47):7513-6.

Gartia MR, Misra SK, Ye M, Schwartz-Duval A, Plucinski L, Zhou X, Kellner D, Labriola LT, Pan D. Point-of-service, quantitative analysis of ascorbic acid in aqueous humor for evaluating anterior globe integrity. Sci Rep. 2015 Nov 3;5:16011.

Misra SK, Ghoshal G, Gartia MR, Wu Z, De AK, Ye M, Bromfield CR, Williams EM, Singh K, Tangella KV, Rund L, Schulten K, Schook LB, Ray PS, Burdette EC, Pan D. Trimodal Therapy: Combining Hyperthermia with Repurposed Bexarotene and Ultrasound for Treating Liver Cancer. ACS Nano. 2015 Nov 24;9(11):10695-10718.

Mukherjee P, Misra SK, Gryka MC, Chang HH, Tiwari S, Wilson WL, Scott JW, Bhargava R, Pan D. Tunable Luminescent Carbon Nanospheres with Well-Defined Nanoscale Chemistry for Synchronized Imaging and Therapy. Small. 2015 Sep;11(36):4691-703.

Misra SK, Jensen TW, Pan D. Enriched inhibition of cancer and stem-like cancer cells via STAT-3 modulating niclocelles. Nanoscale. 2015 Apr 28;7(16):7127-32.

Schirra CO, Senpan A, Roessl E, Thran A, Stacy AJ, Wu L, Proska R, Pan D. Second Generation Gold Nanobeacons for Robust K-Edge Imaging with Multi-Energy CT. J Mater Chem. 2012 Jan 1;22(43):23071-23077.

Wu L, Luderer M, Yang X, Swain C, Zhang H, Nelson K, Stacy AJ, Shen B, Lanza GM, Pan D. Surface passivation of carbon nanoparticles with branched macromolecules influences near infrared bioimaging. Theranostics. 2013 Aug 14;3(9):677-86.

Kim B, Schmieder AH, Stacy AJ, Williams TA, Pan D. Sensitive biological detection with a soluble and stable polymeric paramagnetic nanocluster. J Am Chem Soc. 2012 Jun 27;134(25):10377-80.